Unlocking the Potential
of Biologic Medicine

Harnessing the Biology of Sphingolipids

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Transcera is a founder-led, venture-backed biotech company

About Transcera

Transcera is a founder-led, venture-backed biotech company formed in 2021 to translate discoveries from the Lencer and Chinnapen labs at Harvard Medical School and Boston Children’s Hospital. The company is based in Kendall Square, Cambridge, Massachusetts.
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Transforming Biologic
Medicine Delivery

— 01

The Problem

Absorption and distribution of biologic drug molecules within the body are limited by epithelial and endothelial cell barriers, such as the intestinal mucosa and the blood-brain barrier. Traditional delivery approaches have failed to overcome these obstacles.

— 02
Viruses and toxins in nature evolved mechanisms

A Solution from Nature

Viruses and toxins in nature evolved mechanisms to bypass cellular barriers. The Lencer lab discovered one of these mechanisms, sphingolipid membrane trafficking, and learned how to coopt it for drug delivery. Transcera leverages this biology to make therapeutic peptides, proteins, and oligonucleotides with enhanced pharmacokinetic and pharmacodynamic properties.

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Oral Biologics

Leveraging transcytosis to enable mucosal absorption of large molecule therapeutics, eliminating the need for injections and improving accessibility.

Amplified Biodistribution

Our fully synthetic lipid vehicles can be tuned to enhance uptake and retention in different tissues, providing a more potent and durable effect.

Intracellular Delivery

Advancing intracellular delivery techniques to ensure precise and effective targeting of therapeutic molecules, promising enhanced treatments for a range of health conditions.

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Meet Our Team

Wayne Lencer, MD

Academic Co-Founder

Hunter Goble, MBA

Co-Founder & CEO

Justin Wolfe, PhD

Co-Founder & CSO

Deepa Patil, PhD

Scientist II

Christina McGuire, PhD

Principal Scientist

Joanna Podkalicka, PhD

Senior Scientist

Jiaqian Li, PhD

Scientist

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Unlocking the Potential of Biologic Medicine.

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